A New Perspective on Preventing and Curing COVID-19 Patients: Encouraging Medical Teams to Contact Cured People Treated with Chlorine Dioxide Solution (CDS)

A New Perspective on Preventing and Curing COVID-19 Patients: Encouraging Medical Teams to Contact Cured People Treated with Chlorine Dioxide Solution (CDS)

Mediterranean BioMedical Journals Integrative Journal of Medical Sciences 2020, Volume 7, 229 DOI: 10.15342 / ijms.7.229

Enrique A. Martínez Catholic University of the North, Coquimbo, Chile

SUMMARY This article is written to encourage medical teams around the world to contact COVID-19 patients already treated with Chlorine Dioxide Solution (CDS), a water soluble gas. To also contact the medical teams that accompany the study cases in order to verify the real health conditions of the patients. Finally, the question is asked whether CDS should be tested in their respective local healthcare settings, as it is low cost, appears highly effective against all viral infections and has almost no side effects. KEY WORDS: CDS; Chlorine Dioxide Solution; COVID-19; Declaration of Helsinki. Correspondence: Dr Martinez Enrique, Foyer de Charité de Provence, BP63, Lambesc, 13410, France. Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it. © Copyright 2020

Martinez EA. This is an open access article distributed under Creative Commons Attribution 4.0 International, which allows unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. As of June 2020, the COVID-19 pandemic has caused more than 4,3 million confirmed cases and more than 290.000 deaths worldwide. The pandemic has changed the world forever. Social, economic, environmental and health changes [1] have strongly questioned how humanity can respond to this and other invasive threats so rapidly. This article aims to encourage medical teams to follow what has been done in some countries where COVID19 patients have been successfully treated with CDS (Chlorine Dioxide Solution). bags against viruses such as HIV and other pathogens [3], why not try it in patients with COVID-19 having then so few treatment alternatives. These trials resulted in the recovery of all patents treated in just four days of treatment [2]. Taking into account the declaration of the Helsinki World Medical Association - section No. 37, which states that "Every doctor is authorized to use new or unproven preventive, diagnostic and therapeutic procedures", and the fact that thousands of patients who suffered from this COVI-19 infection were dying, in May 2020, Ecuadorian doctors decided to test chlorine dioxide in solution to treat 104 patients. These patients signed, under notarial verification, an authorization and discharge to receive this treatment [2]. 

They used the CDS recognizing that, on the one hand, viruses are known to be absolutely sensitive to oxidation and, on the other hand, if it works in human blood

What is the CDS? This gas molecule (ClO2) is highly soluble in water. Once in solution, the gas gives a yellowish color, by physical refraction. To date, it has not been introduced in the conventional pharmacopoeia as an active ingredient, although since 1994 it has been used on a mandatory basis to disinfect and preserve blood bags for transfusions, following its patented use as an antiviral agent in 1991 [3]. It is also used in most of the bottled waters suitable for consumption, as it does not leave toxic residues. Furthermore, the gas evaporates at temperatures above 11ºC.

How does CDS work on viruses (and bacteria)? The small size of viruses (and bacteria) allows oxygen to oxidize them very quickly, without affecting the larger cells of living organisms infected by viruses or bacteria [4]. The precise action is on nucleic acids. Nucleic acids, DNARNA, are made up of a chain of purine and pyrimidine bases, guanine (G), cytosine (C), adenine (A), and thymine / uracil. 2020; 7: 2 p 1 Integr J Med SciMartinez EA Perspective for preventing and curing COVID-19 (T / U) patients. Guanine bases, found in both RNA and DNA, are very sensitive to oxidation, forming 8oxoguanine as a by-product of it. Therefore, when the ClO2 molecule comes into contact with guanine and oxidizes it, leading to the formation of 8-oxoguanine, it then blocks the replication of the viral nucleic acid by base pairing. Although the replication of the protein capsid may continue, the formation of the fully functional virus is blocked by oxidation thanks to ClO2.

The oxygen in ClO2 seems to move faster in the bloodstream as it does not need hemoglobin to be transported. This hypothesis would explain, according to the recorded data, why patients treated with CDS and suffering from COVID-19, recovered their oxygen saturation levels so quickly [2]. In the past, this gas and related molecules have been tested against various viruses, bacteria but also other larger parasites such as fungi and yeast [5]. Furthermore, CDS has extremely low toxicity against humans in the short and long term (5,6,7,8,9,10). These studies did not show harmful effects on physiological characteristics such as pulse, respiratory rate and temperature, or on biochemical parameters such as glucose, urea nitrogen, phosphates, alkaline phosphatase, transaminases or thyroid excretions. Neither hemolysis nor anemia were detected at doses of 24 ppm per day for two weeks. Chlorine dioxide was safe even for drinking water, as demonstrated in a study of 198 people for 115 days [11]. The global overreaction applied on people such as social blockade seems to cause more problems than the virus itself [12]. The few treatments still available, the high costs


REFERENCES [1] Nicola M, Alsafi Z, Sohrabi C, Kerwan A, Al-Jabir A, Iosifidis C, Agha M, Agha R. The socio-economic implications of the coronavirus pandemic (COVID-19): A review. Int J Surg. 2020; 78: 185-193. Available at: (visited on September 17th, 2020).

[2] Over 100 [people] Recovered from Covid-19 with CDS by Physicians of the Ecuadorian Association of Integrated Medicine, AEMEMI (Asociación Ecuatoriana de Médicos Expertos en Medicina Integrativa, according to the Spanish acronym). Available at: 7 / 100Recovered-Aememi-1: 7 and (visited on September 17th, 2020). The data of this study on 104 patients is on the journal website and also available upon author request. [3] Kross RD, Scheer DI. Composition and procedure for disinfecting blood and blood components. Available at:  1991 (visited on September 17th, 2020).

[4] Noszticzius Z, Wittmann M, Kály-Kullai K, Beregvári Z, Kiss I, Rosivall L, et al. Chlorine Dioxide Is a SizeSelective Antimicrobial Agent. 2013. PLoS ONE 8 (11): e79157. Available at:  (visited on September 17th, 2020).

[5] Barry Wintner B, Contino A, O'Neill G. Chlorine Dioxide, Part 1: A Versatile, High-Value Sterilant for the Biopharmaceutical Industry. BioProcess International Technical December 2005. Pp. 42-46. Available at: rt_1_A_Versatile_High_Value_Sterilant_for_the_Biophar maceutical_Industry (visited on September 17th, 2020). and low speed of vaccines development all seems to indicate that alternative treatments and even nutrition factors 

[6] Patel Y, Wong D. Toxicological review of chlorine dioxide and chlorite. EPA / 635 / R-00/007. 2000. Available at: toxreviews / 0648tr.pdf (visited on September 17th, 2020).

[7] Lubbers, JR; Chauhan, S; Bianchine, JR. Controlled clinical evaluations of chlorine dioxide, chlorite and chlorate in man. Fundam Appl Toxicol 1: 334-338. (1981)

[8] Lubbers, JR; Chauhan, S; Bianchine, JR. Controlled clinical evaluations of chlorine dioxide, chlorite and chlorate in man. Environ Health Perspect 46: 57-62. (1982) [9] Lubbers, JR; Chauhan, S; Miller, JK, Bianchine, JR The effects of chronic administration of chlorine dioxide, chlorite and chlorate to normal healthy adult male volunteers. J Environ Pathol Toxicol Oncol 5: 229-238. (1984a).

[10] Lubbers, JR; Chauhan, S; Miller, JK; Bianchine, JR. The effects of chronic administration of chlorite to glucose-6phosphate dehydrogenase deficient healthy adult male volunteers. J Environ Pathol Toxicol Oncol 5: 239-242. (1984b).

[11] Michael, GE, Miday, RK, Bercz, JP, Miller, RG, Greathouse, DG, Kraemer, DF, & Lucas, JB. Chlorine Dioxide Water Disinfection: A Praspective Epidemiology Study, Archives of Environmental Health: An International Journal, 36: 1, 20-27, DOI: 10.1080 / 00039896.1981.10667601 (1981)

[12] Boretti, A. Sustainable Post Covid19 Lockdown Strategy Through Evidence-Based Policy: Analysis of Covid19 Fatalities Across Europe. Integr J Med Sci 2020, Volume 7, ID 172 DOI: 10.15342 / ijms.7.172 [13] Zhang Y., Chen, G. Nutritional Considerations in COVID19 Pandemic. Integrative Journal of Medical Sciences 2020, Volume 7, ID 198. DOI: 10.15342 / ijms.7.198.


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