1.0Andreas Kalckerhttps://andreaskalcker.com/en/andreasKalckerWqhttps://andreaskalcker.com/en/author/andreaskalckerwq/rich600338<blockquote class="wp-embedded-content" data-secret="7eeYqb1jqZ"><a href="https://andreaskalcker.com/en/mechanism-of-action/">Mechanism of action</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://andreaskalcker.com/en/mechanism-of-action/embed/#?secret=7eeYqb1jqZ" width="600" height="338" title="“Mechanism of action” — Andreas Kalcker" data-secret="7eeYqb1jqZ" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script> /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); //# sourceURL=https://andreaskalcker.com/wp-includes/js/wp-embed.min.js </script> Pharmacokinetics of chlorine dioxide in the form of CDS Pharmacokinetics studies the processes through which a drug passes through the body, focusing on the pattern and rate of absorption, distribution, metabolism and elimination. The actions of all drugs are influenced by their pharmacokinetics, so it is important to understand pharmacokinetics in order to make informed clinical decisions. This is achieved through the following points:   Absorption: how the drug enters the bloodstream. Distribution: how the drug is distributed throughout the body tissues. Metabolism: how the drug is processed and transformed in the body. Excretion: how the drug is eliminated from the body. CDS release, CDS is a chlorine dioxide gas extremely soluble in water, due to its small size and V-shaped water molecule-like structure, able to create an ensemble due to a molecular angle of 117.6º that matches the 104.45º of H2O in such a way that it creates hexagonal structures.    This is a very interesting electromolecular effect,  and it can be observed in microscopy after applying chlorine dioxide in  blood Rouleaux with low oxygen  after a few minutes. This phenomenon is fascinating as it demonstrates the ability of CDS to form ordered, hexagonal structures in a biological environment.    Furthermore, the ability of CDS to rapidly dissolve in water and create these unique assemblies demonstrates its potential to be used in various fields, such as medicine and biotechnology. Studies have shown that CDS has antimicrobial oxidant and as well antioxidant properties due to its ORP oxidation-reduction potential (e.g., against OH* hydroxyl  radicals, despite being an oxidant). This makes it a promising candidate for the development of new medical treatments.   In summary, CDS is a fascinating substance with unique and promising scientific and medical qualities.   Absorption of CDS Once an amount of 30 mg of CDS dissolved in water has been ingested (protocol C), the gas is released by evaporation in the stomach due to its temperature of approximately 36.5º C. It is important to keep in mind that CDS evaporates at 11º degrees Celsius, unlike sodium chlorite which evaporates at 170°C.   Since the human body contains a significant amount of water, the mucous membranes of the stomach absorb this dissolved gas immediately. Because of its size, CDS easily diffuse  the stomach walls according to Fick’s gas diffusion laws and moves through the blood system into the interstitium. Subsequently, it is transported to all parts of the body where water is present, being an extremely small molecule compared to the macromolecules of conventional drugs. Distribution in the body Thanks to its high solubility and small size of only 160 nm in water without hydrolysis, the CDS molecule is distributed randomly in the body, following Fick’s second law of conservation of mass in the absence of any chemical reaction.   Chlorine dioxide (ClO2) transports oxygen: 1 mg of ClO2 contains 0.48 mg of oxygen. 1 mg of ClO2 is equivalent to 1.49 x 10-5 moles. 1 mg of ClO2 potentially contains 8.97 x 1018 molecules of O2. 1 mole of O2 occupies 22400 ml under normal conditions. 1 mg of ClO2 can potentially release 0.334 ml of O2. Each ml of concentrated 0.3% CDS (3000 ppm) contains 3 mg of ClO2. The amount of oxygen carried by chlorine dioxide is of great interest. It is pertinent to mention that the molecular weight of ClO2 is 67 g/mol, while the molecular weight of O2 is 32 g/mol. Therefore, oxygen constitutes 48% of the molecular weight of ClO2. In this sense, it can be inferred that approximately 0.48 mg of oxygen is found in 1 mg of ClO2.   Considering that 1 mg of ClO2 is equivalent to 1.49 x 10-5 moles, it can be deduced that in 1 mg of ClO2 there are potentially about 8.97 x 1018 molecules of O2. Under normal conditions, 1 mole of O2 occupies 22.400 ml. Therefore, in 1 mg of ClO2 could release approximately 0.334 ml of O2. Considering protocol C for covid-19, which consists of 10 ml of CDS at 3000 ppm, each ml of concentrated 0.3% CDS contains 3 mg of ClO2.   It is relevant to note that 1 ml of CDS can release 1.44 mg of O2 an amount equivalent to 1 ml of dissolved O2 in plasma. This figure is similar to the oxygen carried by 0.72 grams of hemoglobin under a partial pressure of oxygen of 100%. Therefore, 10 ml of CDS could provide 10 ml of molecular oxygen in blood after fully reacting in approximately 2-3 hours. It is important to emphasize that oxygen binds to the chlorine dioxide molecule without being consumed, until it reaches the problem area and dissociates in the presence of excess protons, as is the case with coronavirus capsids, which are oxidized by denaturation. In this way, oxygen first reaches the most acidic cells and their compromised mitochondria in the body, then eliminates pathogens or acidic toxins and restores pH balance.   A beneficial side effect of this is cellular oxygenation. In relation to the amount of oxygen present in the blood, it is relevant to mention the partial pressure of oxygen, known as PO2. In the pulmonary alveoli, PO2 is 100 Torr, while in the capillaries it is 40 Torr. In interstitial tissue, PO2 is only 10-20 Torr, at the cell membrane level it is 10 Torr and in the cell cytosol it is 2 Torr. In the mitochondria, the PO2 is only about 0.2 Torr. 1 ml of CDS releases 1.44 mg of O2, equivalent to 1 ml of dissolved O2 in plasma. 10 ml of CDS can provide 10 ml of molecular oxygen in blood after fully reacting within 2 hours.   Oxygen is bound to the chlorine dioxide molecule without being consumed and dissociates in the presence of excess protons in the problem area. The oxygen reaches the most acidic cells and their compromised mitochondria first, and the chlorine ion eliminates pathogens or acidic toxins and restores pH balance. A beneficial side effect is cellular oxygenation.   When we breathe oxygen diffuses through the capillary bed of the alveoli, 97% is bound to hemoglobin, while only the remaining 3% remains dissolved in the plasma. Red blood cells function as oxygen batteries that release oxygen mainly in the presence of lactic acid, ... Read morehttps://andreaskalcker.com/wp-content/uploads/2023/08/O2-Bindungskurve.png