{"version":"1.0","provider_name":"Andreas Kalcker","provider_url":"https:\/\/andreaskalcker.com\/en\/","author_name":"andreasKalckerWq","author_url":"https:\/\/andreaskalcker.com\/en\/author\/andreaskalckerwq\/","title":"Mechanism of action","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"hkzu7NfSMP\"><a href=\"https:\/\/andreaskalcker.com\/en\/mechanism-of-action\/\">Mechanism of action<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/andreaskalcker.com\/en\/mechanism-of-action\/embed\/#?secret=hkzu7NfSMP\" width=\"600\" height=\"338\" title=\"&#8220;Mechanism of action&#8221; &#8212; Andreas Kalcker\" data-secret=\"hkzu7NfSMP\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script>\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/\/# sourceURL=https:\/\/andreaskalcker.com\/wp-includes\/js\/wp-embed.min.js\n<\/script>\n","description":"Pharmacokinetics of chlorine dioxide in the form of CDS Pharmacokinetics studies the processes through which a drug passes through the body, focusing on the pattern and rate of absorption, distribution, metabolism and elimination. The actions of all drugs are influenced by their pharmacokinetics, so it is important to understand pharmacokinetics in order to make informed clinical decisions. This is achieved through the following points: \u00a0 Absorption: how the drug enters the bloodstream. Distribution: how the drug is distributed throughout the body tissues. Metabolism: how the drug is processed and transformed in the body. Excretion: how the drug is eliminated from the body. CDS release, CDS is a chlorine dioxide gas extremely soluble in water, due to its small size and V-shaped water molecule-like structure, able to create an ensemble due to a molecular angle of 117.6\u00ba that matches the 104.45\u00ba of\u00a0H2O\u00a0in such a way that it creates hexagonal structures. \u00a0 \u00a0This is a very interesting electromolecular effect,\u00a0 and it can be observed in microscopy after applying chlorine dioxide in\u00a0 blood Rouleaux with low oxygen\u00a0 after a few minutes. This phenomenon is fascinating as it demonstrates the ability of CDS to form ordered, hexagonal structures in a biological environment.\u00a0 \u00a0 Furthermore, the ability of CDS to rapidly dissolve in water and create these unique assemblies demonstrates its potential to be used in various fields, such as medicine and biotechnology. Studies have shown that CDS has antimicrobial oxidant and as well antioxidant properties due to its ORP oxidation-reduction potential (e.g., against OH* hydroxyl\u00a0 radicals, despite being an oxidant). This makes it a promising candidate for the development of new medical treatments. \u00a0 In summary, CDS is a fascinating substance with unique and promising scientific and medical qualities. \u00a0 Absorption of CDS Once an amount of 30 mg of CDS dissolved in water has been ingested (protocol C), the gas is released by evaporation in the stomach due to its temperature of approximately 36.5\u00ba C. It is important to keep in mind that CDS evaporates at 11\u00ba degrees Celsius, unlike sodium chlorite which evaporates at 170\u00b0C. \u00a0 Since the human body contains a significant amount of water, the mucous membranes of the stomach absorb this dissolved gas immediately. Because of its size, CDS easily diffuse\u00a0 the stomach walls according to Fick&#8217;s gas diffusion laws and moves through the blood system into the interstitium. Subsequently, it is transported to all parts of the body where water is present, being an extremely small molecule compared to the macromolecules of conventional drugs. Distribution in the body Thanks to its high solubility and small size of only 160 nm in water without hydrolysis, the CDS molecule is distributed randomly in the body, following Fick&#8217;s second law of conservation of mass in the absence of any chemical reaction. \u00a0 Chlorine dioxide (ClO2) transports oxygen: 1 mg of\u00a0ClO2\u00a0contains 0.48 mg of oxygen. 1 mg of\u00a0ClO2\u00a0is equivalent to 1.49 x 10-5 moles. 1 mg of\u00a0ClO2\u00a0potentially contains 8.97 x 1018 molecules of\u00a0O2. 1 mole of\u00a0O2\u00a0occupies 22400 ml under normal conditions. 1 mg of\u00a0ClO2\u00a0can potentially release 0.334 ml of\u00a0O2. Each ml of concentrated 0.3% CDS (3000 ppm) contains 3 mg of\u00a0ClO2. The amount of oxygen carried by chlorine dioxide is of great interest. It is pertinent to mention that the molecular weight of\u00a0ClO2\u00a0is 67 g\/mol, while the molecular weight of\u00a0O2\u00a0is 32 g\/mol. Therefore, oxygen constitutes 48% of the molecular weight of\u00a0ClO2. In this sense, it can be inferred that approximately 0.48 mg of oxygen is found in 1 mg of\u00a0ClO2. \u00a0 Considering that 1 mg of\u00a0ClO2\u00a0is equivalent to 1.49 x 10-5 moles, it can be deduced that in 1 mg of\u00a0ClO2\u00a0there are potentially about 8.97 x 1018 molecules of\u00a0O2. Under normal conditions, 1 mole of\u00a0O2\u00a0occupies 22.400 ml. Therefore, in 1 mg of\u00a0ClO2\u00a0could release approximately 0.334 ml of\u00a0O2. Considering protocol C for covid-19, which consists of 10 ml of CDS at 3000 ppm, each ml of concentrated 0.3% CDS contains 3 mg of\u00a0ClO2. \u00a0 It is relevant to note that 1 ml of CDS can release 1.44 mg of\u00a0O2 an amount equivalent to 1 ml of dissolved\u00a0O2\u00a0in plasma. This figure is similar to the oxygen carried by 0.72 grams of hemoglobin under a partial pressure of oxygen of 100%. Therefore, 10 ml of CDS could provide 10 ml of molecular oxygen in blood after fully reacting in approximately 2-3 hours. It is important to emphasize that oxygen binds to the chlorine dioxide molecule without being consumed, until it reaches the problem area and dissociates in the presence of excess protons, as is the case with coronavirus capsids, which are oxidized by denaturation. In this way, oxygen first reaches the most acidic cells and their compromised mitochondria in the body, then eliminates pathogens or acidic toxins and restores pH balance. \u00a0 A beneficial side effect of this is cellular oxygenation. In relation to the amount of oxygen present in the blood, it is relevant to mention the partial pressure of oxygen, known as\u00a0PO2. In the pulmonary alveoli,\u00a0PO2\u00a0is 100 Torr, while in the capillaries it is 40 Torr. In interstitial tissue,\u00a0PO2\u00a0is only 10-20 Torr, at the cell membrane level it is 10 Torr and in the cell cytosol it is 2 Torr. In the mitochondria, the\u00a0PO2\u00a0is only about 0.2 Torr. 1 ml of CDS releases 1.44 mg of\u00a0O2, equivalent to 1 ml of dissolved\u00a0O2\u00a0in plasma. 10 ml of CDS can provide 10 ml of molecular oxygen in blood after fully reacting within 2 hours. \u00a0 Oxygen is bound to the chlorine dioxide molecule without being consumed and dissociates in the presence of excess protons in the problem area. The oxygen reaches the most acidic cells and their compromised mitochondria first, and the chlorine ion eliminates pathogens or acidic toxins and restores pH balance.\u00a0A beneficial side effect is cellular oxygenation. \u00a0 When we breathe oxygen diffuses through the capillary bed of the alveoli, 97% is bound to hemoglobin, while only the remaining 3% remains dissolved in the plasma. Red blood cells function as oxygen batteries that release oxygen mainly in the presence of lactic acid, ... 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