Publications in Humans

Peer-Reviewed Publications on CDS in Humans and Related Subjects

On this page you will find links to research on chlorine dioxide that is directly related to humans and does not contain industrial applications or water treatment. This collection is not complete, but includes the most relevant scientific studies on chlorine dioxide to date. 

Essential Overview April 2024

1. International consensus report on SARS-Cov-2, COVID-19 and the immune system: an orthomolecular view
International Society for Orthomolecular Medicine
ISSN:0834-4825 2.

https://isom.ca/article/an-international-consensus-report-on-sars-cov-2-covid-19-and-the-immune-system-an-orthomolecular-view/

 

2. Chlorine dioxide in COVID-19: Hypothesis on possible molecular mechanism of action in SARS-CoV-2
Molecular Medicine and Genetics
ISSN: 1747-0862
https://www.hilarispublisher.com/abstract/chlorine-dioxide-in-covid19-hypothesis-about-the-possible-mechanism-of-molecular-action-in-sarscov2-52824.html

 

3. A New Perspective for Prevention and for Curing COVID-19 Patients: Encouraging Medical Teams to Contact Cured Persons Treated with Chlorine Dioxide Solution (CDS)
Integrative Medical Sciences Conference
ISSN: 2658-8218
https://mbmj.org/index.php/ijms/article/view/229

 

4. Determination of the efficacy of chlorine dioxide in the treatment of COVID-19
Molecular Medicine and Genetics
ISSN: 1747-0862
https://www.hilarispublisher.com/open-access/determination-of-the-effectiveness-of-chlorine-dioxide-in-the-treatment-of-covid19-67319.html

 

5. Chlorine dioxide as an alternative treatment of COVID-19
Journal of Infectious Diseases and Therapy.
ISSN: 2332-0877
https://www.omicsonline.org/open-access/chlorine-dioxide-as-an-alternative-treatment-for-covid19.pdf

 

6. A retrospective observational study of the efficacy of chlorine dioxide for the prophylaxis of COVID19-like symptoms in relatives living with COVID19 patients
INTERNATIONAL JOURNAL OF MULTIDISCIPLINARY RESEARCH AND ANALYSIS
ISSN: 2643-9875
http://ijmra.in/v4i8/2.php

 

7. Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor
Nature communications chemistry selections
ISSN :2188-5044
https://pubmed.ncbi.nlm.nih.gov/32917884/

 

8. COVID19 Long-term effects in patients treated with chlorine dioxide
International Journal of Multidisciplinary Research and Analysis
ISSN :2643-9875
http://ijmra.in/v4i8/14.php

 

9. Comparative study of hyperpure chlorine dioxide with two other irrigants in relation to periodontal ligament stem cell viability Springer
ISSN: 2627-8626
https://link.springer.com/article/10.1007/s00784-020-03618-5

 

10. Eradication of MRSA by chlorine dioxide Journal of bacteriology and mycology
ISSN: 2469-2786
https://medcraveonline.com/JBMOA/JBMOA-09-00306.pdf

 

11. Evaluation of the efficacy and safety of a chlorine dioxide solution
International Conference on Environmental Research and Public Health
ISSN: 1660-4601
https://www.mdpi.com/1660-4601/14/3/329/htm

 

12. Chlorine dioxide is a size-selective antimicrobial agent
PLOS ONE
ISSN: 1932-6203
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079157

 

13. Inactivation of influenza virus hemagglutinin by chlorine dioxide: oxidation of the conserved residue tryptophan 153 at the receptor binding site Journal of General Virology
ISSN: 1465-2099
https://www.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.044263-0

 

14. Can chlorine dioxide prevent the spread of coronaviruses or other
viral infections? Medical hypotheses Akadémiai Kiadó
ISSN: 2061-4705
https://akjournals.com/view/journals/2060/107/1/article-p1.xml

 

15. Inactivation of human and simian rotaviruses by chlorine dioxide
American Society for Microbiology (“ASM”)
ISSN: 0196-8254
https://journals.asm.org/doi/10.1128/aem.56.5.1363-1366.1990

 

16. Controlled clinical evaluations of chlorine dioxide, chlorite, and chlorate in man
Environmental Health Perspectives (EHP)
ISSN: 1542-6351
https://ehp.niehs.nih.gov/doi/10.1289/ehp.824657

 

17. Clinical and microbiological efficacy of chlorine dioxide in the management of
chronic atrophic candidiasis: an open-label study Int Dent J. 2004 Jun;54(3):154-8. Mohammad AR, Giannini PJ, Preshaw PM, Alliger H. doi: 10.1111/j.1875-595x.2004.tb00272.x. PMID: 15218896.
https://www.sciencedirect.com/science/article/pii/S0020653920350929?via%3Dihub

 

18. Protein Denaturation by Chlorine Dioxide:Oxidative Modification of Tryptophan and
tyrosine Residues Biochemistry ACS PUB
ISSN: 1044-5099
https://pubs.acs.org/doi/full/10.1021/bi061827u

 

19. Chlorine dioxide inhibits porcine reproductive and respiratory syndrome virus replication by blocking viral adhesion Elsevier
ISSN :0922-3444
https://www.sciencedirect.com/science/article/abs/pii/S1567134818305549?via%3Dihub

 

20. Effects of chlorine dioxide on oral hygiene: a systematic review and meta-analysis
Current pharmaceutical design
ISSN :1873-4286
https://www.eurekaselect.com/article/106659

 

21. Kinetics and Mechanisms of Chlorine Dioxide and Chlorite Oxidations of Cysteine and Glutathione Inorg. Chem. ACS PUB
ISSN: 1044-5099
https://pubs.acs.org/doi/full/10.1021/ic0609554

 

22. The 40-80 nt region in the 50 -NCR of the genome is a critical target for inactivating poliovirus by chlorine dioxide
Journal of Medical Virology
ISSN :1096-9071
https://pubmed.ncbi.nlm.nih.gov/6295277/

Research on the virucidal activity of chlorine dioxide. Experimental data on feline calicivirus, HAV and Coxsackie B5 Journal of preventive medicine and hygiene ISSN:1121-2233
https://pubmed.ncbi.nlm.nih.gov/18274345/

 

23. Kinetics and mechanism of bacterial disinfection by chlorine dioxide American Society for Microbiology
ISSN: 0569-7603
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546889/

 

24. Resistance study of severe acute respiratory syndrome-associated coronavirus
Elsevier
ISSN :0922-3444
https://www.sciencedirect.com/science/article/pii/S0166093405000649?via%3Dihub

 

25. Protective effect of chlorine dioxide at low concentration Journal of General Virology
ISSN :1465-2099
https://www.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.83393-0

 

26. Can nasal irrigation with chlorine dioxide be considered as a possible alternative therapy for respiratory infectious diseases? The example of COVID-19
https://pubmed.ncbi.nlm.nih.gov/36504072/

 

27. Prevention of infections and tissue repair in skin lesions by treatments
based on a chlorine dioxide solution: case study
https://www.literaturepublishers.org/assets/images/articles/pNf0Sb_ziYD97_60HZa5_3mc6LU_399176.pdf

 

28. COVID-19 spike protein toxicity is a redox switch phenomenon: A new therapeutic approach  Doi.org/10.1016/j.freeradbiomed.2023.05.034
https://www.sciencedirect.com/science/article/pii/S0891584923005014

 

29. Chlorine dioxide and chlorite as treatments for diabetic foot ulcers International Journal of Medicine and MedicalSciences
DOI:10.5897/IJMMS2023.1503
https://www.semanticscholar.org/reader/a29e004fec0292d0bddaa0d616e29a529019a34b

 

30. Case report: compassionate application of chlorine dioxide-based solution in a patient with metastatic prostate cancer Health, Science and Technology 2024
DOI: https://doi.org/10.56294/saludcyt2024699

 

31. Eradication of antibiotic-resistant E. coli, S. aureus, K. pneumoniae, S. pneumoniae, A.
baumannii and P. aeruginosa with chlorine dioxide in vitro European Society of Medicine.
https://esmed.org/MRA/mra/article/view/4218

32. Klinischer Fall: Auflösung der pathologischen Fraktur eines metastasierten Non-Hodgkin-Lymphoms mit einer Compassionate-Therapie. Manuel Aparicio-Alonso, Verónica Torres-Solórzano
https://revista.saludcyt.ar/ojs/index.php/sct/article/view/830/1584

33. Intratumoral delivery of chlorine dioxide harnesses its ROS-like properties: a new approach for effective anticancer therapy.

https://www.biorxiv.org/content/10.1101/2023.11.24.568512v1

34. Pain Comparison with Visual Analog Scale (EVA) inPatients with Acute Necrotizing Ulcerative Gingivitis (ANUG) and Wisdom Pericoronitis during Chlorine Dioxide Treatments.

https://www.hilarispublisher.com/open-access/pain-comparison-with-visual-analog-scale-eva-inpatients-with-acute-necrotizing-ulcerative-gingivitisanug-and-wisdom-pericoronitis–86735.html